Co-pay Support for Improved Access to Medication

To help ensure patients have access to the medication they need, Valeant Pharmaceuticals North America LLC is pleased to offer the Valeant Coverage Plus program (VCPP).

Program benefits include:
  • Program representatives that will help you identify the best cost-saving option specific to your needs
  • Ability to have your medication delivered to your home
  • Refill tracking and notification services (optional)

The VCPP offers assistance to patients receiving DEMSER® (Metyrosine), Syprine® (trientine hydrochloride), or Cuprimine® (Penicillamine) Capsules.

Learn More About the Coverage Plus Program and

IMPORTANT SAFETY INFORMATION

  • Do not use Demser if you are allergic to metyrosine, its active ingredient.
  • Life-threatening high blood pressure and/or life-threatening abnormal heart rhythms may occur during anesthesia and surgery. If you are planning to have surgery under anesthesia, be sure to let your surgeon and anesthesiologist know that you are taking Demser.
  • Demser may add to the sedative effects of alcohol and other medicines that affect the central nervous system such as hypnotics, sedatives and tranquilizers.
  • If you have liver or kidney disease, your doctor may order periodic laboratory tests if you take Demser for a long period of time.
  • Be careful when engaging in activities requiring mental alertness and motor coordination such as driving a motor vehicle or operating machinery since a common side effect of Demser is moderate to severe sedation.
  • It is important to drink a lot of water while you are taking Demser.
  • Demser can add to certain side effects of medications known as phenothiazines, or to the medication known as haloperidol. These side effects may include movement disorders and/or muscle spasms. Tell your doctor about all medications that you take.
  • The most common side effect to Demser is moderate to severe sedation. Other commonly reported side effects are drooling, speech difficulty and tremor in approximately 10 percent of patients, occasionally accompanied by trismus (lockjaw, a difficulty opening or closing the mouth) and Parkinsonism. Anxiety, depression, hallucinations, disorientation, and confusion may occur. Diarrhea occurs in about 10 percent of patients and may be severe.

INDICATIONS AND USAGE

DEMSER (Metyrosine) is used for the treatment of patients with pheochromocytoma, a tumor of the adrenal glands, to:

  • prepare patients for surgery,
  • manage patients when surgery cannot be performed,
  • treat patients long-term who have malignant pheochromocytoma

» Click here to see full Prescribing Information

You are encouraged to report negative side effects of prescription drugs to FDA.
Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.

Learn More About the Coverage Plus Program and

Important Safety Information

  • Do not take Syprine if you are allergic to it or any parts of the formulation.
  • You should remain under regular medical supervision the entire time you are taking Syprine. Your doctor should regularly check to see if you have iron deficiency anemia. This is particularly important for women.
  • Take Syprine on an empty stomach, at least one hour before a meal or two hours after a meal and at least one hour apart from any other drug, food, or milk. The capsules should be swallowed whole with water and should not be opened or chewed. For the first month of treatment, take your temperature every night, and report any symptom such as fever or skin rash to your doctor.
  • Tell your doctor if you are pregnant, plan to become pregnant, or are nursing.
  • The following adverse reactions have been reported from a clinical study: iron deficiency and a condition affecting the immune system known as systemic lupus erythematosus. In addition, the following adverse reactions have been reported in marketed use: abnormal or uncontrolled muscle contractions, muscle spasm and an immune disease affecting muscles known as myasthenia gravis.
  • Do not take mineral supplements because they may block the absorption of Syprine.

INDICATIONS AND USAGE

SYPRINE® (trientine hydrochloride) is used to treat Wilson's disease in patients who cannot take the medication known as penicillamine. Wilson's disease is a condition where the body stores too much copper. SYPRINE is not recommended to treat cystinuria (a condition where a protein known as cystine is excreted into the urine), rheumatoid arthritis, or a disease affecting the bile ducts in the liver known as biliary cirrhosis.

» Click here for full Prescribing Information.

You are encouraged to report negative side effects of prescription drugs to FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.

Learn More About the Coverage Plus Program and

Important Safety Information

WARNING: You should be under the close supervision of your doctor when you are taking CUPRIMINE. Report any side effects promptly to your doctor.
  • Do not take Cuprimine if you are pregnant unless you are taking Cuprimine to treat Wilson’s disease (too much copper in the body) or cystinuria (too much protein in the urine). Mothers on therapy with penicillamine should not nurse their infants.
  • Cuprimine can cause serious blood disorders, and some can be fatal. If you have had aplastic anemia (anemia due to lack of all blood cells) or agranulocytosis (lack of certain white blood cells) and it was related to taking Cuprimine, you should not take it again.
  • Cuprimine can cause kidney damage and should not be used to treat rheumatoid arthritis if you have a history of kidney disease. If you take Cuprimine to treat cystinuria, routine analysis of your urine may be necessary and you should have an x-ray every year to check for kidney stones.
  • Cuprimine can be associated with fatalities due to other diseases such as Goodpasture’s syndrome (an immune disease that attacks the lungs and kidneys) and myasthenia gravis (an immune disease affecting the muscles). Your doctor may order blood analysis on a regular basis.
  • Cuprimine can affect how your liver works. Tests to determine how your liver is working should be done regularly.
  • Tell your doctor right away if you experience: blood in your urine, unexplained cough or wheezing, coughing up blood, shortness of breath, muscle weakness, drooping eyelids, double vision, watery blisters on the skin or other rash, fever, joint pain,  swollen lymph nodes, mouth ulcers, or diminished taste.
  • Cuprimine is a drug that has many side effects, and some can be fatal. Other side effects that can occur include serious lung problems, nervous system symptoms, diseases of the skin and mucous membranes known as pemphigus, allergic reactions (including a condition known as drug fever as well as skin rashes), mouth ulcers, and loss of taste. Talk to your doctor if you experience side effects and also about possible side effects that could occur. Ask your doctor or pharmacist for product labeling written for professionals for a full list of potential adverse reactions.
  • Tell your doctor about all other medicines (prescription and over-the-counter,  including vitamins and herbal supplements) that you are taking. Some medicines (such as gold therapy, antimalarial or cancer drugs, oxyphenbutazone or phenylbutazone) should not be used with Cuprimine because they also may cause serious liver and kidney side effects.

INDICATIONS AND USAGE

CUPRIMINE (penicillamine) ) Capsules are used to treat Wilson's disease (a disease where there is too much copper in the body), cystinuria (a disease where an excess amount of certain proteins are in the urine) and in patients with severe, active rheumatoid arthritis who have not had a response to other therapy.

» Click here for full Prescribing Information, including Boxed Warning.

You are encouraged to report negative side effects of prescription drugs to FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.

You are encouraged to report negative side effects of prescription drugs to FDA.
Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.